Cross Campus Initiatives, Centers & Institutes

Learn more about the innovative University of Michigan centers and institutes working on the opioid epidemic with local, state, and national partners.
Cross-Campus CentersDepartment-based Centers

Cross-Campus Initiatives, Centers & Institutes

University of Michigan Precision Health

Precision health uses advanced tools and technology to discover the genetic, lifestyle and environmental factors that influence a population’s health and provides personalized solutions that allow individuals to improve their health and wellness. University of Michigan Precision Health:

  • Provides the right resources and analytic tools to enable a diverse group of researchers to access complex datasets.
  • Actively bridges the full spectrum of precision health:
    • Precision Discovery: Identifying fundamental new knowledge in social, medical, computational and engineering sciences.
    • Precision Treatment: Translating these discoveries into promising treatments for patients.
    • Precision Implementation: Assessing the public health impact of therapies, working with community health systems, policy makers and payers to implement these therapies across the state and nation.

Precision Health at the University of Michigan supports a variety of precision-related research projects — across a broad spectrum of disciplines — occurring at U-M. Our pilot project focuses on opioid prescribing in the pre-surgical setting. University of Michigan Precision Health is focusing on understanding the factors that put people at risk of long-term opioid use so that these patients can be prescribed alternative pain management strategies when having surgery.

University of Michigan Injury Prevention Center

The University of Michigan Injury Prevention Center is a CDC-funded, U-M-supported research program focused on injury prevention. One of its main focus areas is opioid overdose prevention. The Injury Prevention Center addresses opioid overdose prevention by funding numerous research projects to understand and address the epidemic, and educating students, practitioners, and providers on safe opioid prescribing, and effective prevention and treatment strategies.

Edward Domino Center

The goal of the Edward F Domino Research Center is to study opioid addiction at the molecular, cellular level and in animal models. This center was started with funds from Dean Runge. The aim of the center is to understand the addiction process at a neuroscience/animal behavioral level, to identify medications to treat opioid abuse and overdose and design non-addictive analgesic opioids.

Key Leaders: John Traynor, PhD (Pharmacology): Director; Margaret Gnegy, PhD (Pharmacology): outreach/education; Emily Jutkiewicz, PhD (Pharmacology); Manoj Puthenveedu, PhD (Pharmacology); Alan Smrcka, PhD (Pharmacology); Carrie Ferrario, PhD (Pharmacology); Henry Mosberg, PhD (Medicinal Chemistry; College of Pharmacy); Robert Kennedy, PhD (Chemistry,LSI)

Institute for Healthcare Policy and Innovation (IHPI)

IHPI is the nation’s leading university-based institute of health services researchers, with more than 500 faculty members from all three U-M campuses evaluating how healthcare works and how it can be improved, and advising policy makers to inform change. IHPI aims to disrupt the epidemic of prescription opioid misuse and opioid addiction through research and innovative programs on appropriate prescribing, misuse prevention, overdose intervention, and addiction treatment. IHPI members pursue these efforts through various U-M units including the Michigan Opioid Prescribing Engagement Network; the Injury Prevention Center; the Acute Care Research Unit; the Mental Health Innovation, Services and Outcomes Program, as well as the Michigan Surgical Quality Consortium and the VA Center for Clinical Management Research.

Key Leaders: John Ayanian, MD, MPP

Center for the Study of Drugs, Alcohol, Smoking and Health (DASH)

The interdisciplinary center will focus on population trends, prevention, treatment, and care for patients, including those with co-morbid health problems, related to substance use and misuse. The DASH team, which includes interdisciplinary faculty, postdoctoral fellows and graduate students, is committed to advancing knowledge of substance use and its consequences through pioneering scholarship, evidence-based prevention, innovative clinical training and timely public policy and service.


Michigan-OPEN seeks to develop a preventative approach to the opioid epidemic in the state of Michigan. The initiative aims to transform surgical pain management and curb opioid misuse by targeting opioid-naïve patients prior to opioid dependence. Through prevention, intervention, and education, Michigan-OPEN aims to disrupt the epidemic of prescription opioid addiction now affecting every age group – from the nation’s youth to the elderly. Over the next five years, the initiative will increase awareness among surgical patients and providers regarding the risks of prescription opioids, obtain detailed clinical data, and identify and disseminate best practices in post-operative opioid prescribing.

UMSARC (U-M Substance Abuse Research Center)

To promote and extend the knowledge regarding individual, institutional and social mechanisms of substance use/abuse. By applying the University of Michigan’s unique strengths in research and training; we aim to cross disciplinary boundaries, consider innovative questions, develop new research strategies, advance public discourses and develop a greater understanding of substance abuse.

Home institution: U-M School of Public Health

Department-based Centers

University of Michigan Addiction Center (Psychiatry)

The University of Michigan Addiction Center has a three-tiered mission:
1) to conduct clinically-relevant research on the onset, diagnosis, treatment, and clinical course of substance use disorders;
2) to generate and disseminate new knowledge to educate and train the next generation of clinicians and research scientists; and
3) to deliver specialized treatment services for individuals with substance use disorders.

Educational programs

  • Addiction Center Training Program
  • Addiction Psychiatry Fellowship

Ongoing projects on addiction, including opioid-related addiction

Chronic Pain & Fatigue Research Center (Anesthesiology)

The Chronic Pain and Fatigue Research Center (CPFRC) is a multidisciplinary center committed to improving the understanding and management of disorders distinguished by symptoms of chronic pain and fatigue. The CPFRC holds regular education seminars designed to provide patients and their families with the latest information about pain syndromes, as well as guidance on symptom management strategies.