Centralized Pain Phenotype as a Predictor of Opioid Non-Responsiveness

Summary

Performs both opioid PET and fMRI and individuals undergoing knee arthroplasty and hypothesizes that the centralized pain phenotype is characterized by opioid non-responsiveness because the endogenous opioid system is participating in the pathogenesis of centralized pain states.

Status: Ongoing
Funding: NIH/ NIDA
Faculty Engagement: Alexander Tsodikov, Ph.D. Faculty Engagement: Steven Harte, Ph.D. Faculty Engagement: Richard E. Harris, Ph.D.
Category: Research