What We Know

The opioid epidemic, now the deadliest drug crisis in U.S. history, affects a diverse range of individuals—in urban and rural communities, among adolescents and elderly adults, and across all races and socioeconomic sectors.

The Ongoing Severity of the Opioid Crisis

In the U.S., the number of opioid overdose deaths has increased significantly since 1999. In 2022, approximately 81,806 people died from opioid overdoses. This equates to an average of about 224 deaths daily. Opioid overdoses currently account for over 60 percent of all drug overdose deaths nationwide. Economically, the opioid epidemic cost the U.S. economy an estimated $1.5 trillion in 2020, encompassing healthcare expenses, lost productivity, and other related costs.

These updated figures highlight the ongoing severity of the opioid crisis and its profound impact on public health and the economy.

76%
of all drug overdose deaths nationwide

Since 2000, opioid overdose deaths in Michigan have increased significantly.

However, since 2022, these numbers have steadily decreased, highlighting the continued need for effective prevention and intervention strategies. 

In 2000, there were 183 opioid-related deaths
By 2023, this number had risen to 2,287
But in 2024,  there was a 34% decrease to 1,916

In Michigan, this epidemic impacts thousands of residents and their families, friends and communities each day.

Over the past 22 years, the epidemic’s impact in the state has evolved, especially during the COVID-19 pandemic. This pandemic has been associated with opioid-related mortality, and unfortunately, the resources for opioid-related services saw significant decline as well, both in implementation and of evaluation of those resources. However, the University of Michigan (U-M) has continued to work with its partners to urgently address the opioid epidemic in communities throughout the state.

Opioid-Related Deaths in the U.S.:

Daily Deaths

From September 2023-September 2024 there were
224
deaths daily
in the U.S.

Percentage of Drug Overdose Deaths

Opioids were involved
in about
73%
of the 110,700 drug
overdose deaths in 2021